
产品货号:
Z11295
中文名称:
APC5/ANAPC5抗体
英文名称:
Anti-APC5/ANAPC5 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-APC5/ANAPC5 Antibody |
指标别名 | ANAPC5;APC5;Cyclosome subunit 5 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | ANAPC5 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | APC5 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC5.The immunogen is located within amino acids 480 - 530 of APC5. |
计算分子量 | 85kDa |
成分 | APC5 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | APC5 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis.APC5 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C),a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.APC/C is responsible for degrading anaphase inhibitors,mitotic cyclins,and spindle-associated proteins ensuring that events of mitosis take place in proper sequence.The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines,suggesting that they perform their functions as part of a complex.While little is known of APC5,it is thought that APC5 associates with other APC/C components APC1,APC4,and CDC23 interdependently,such that loss of any one subunit reduces binding between the remaining three. |
Uniprot ID | Q9UJX4 |
基因名全称 | Anaphase promoting complex subunit 5 |
蛋白名全称 | Anaphase promoting complex subunit 5 |
推荐稀释比 | APC5 antibody can be used for detection of APC5 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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