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产品目录

APC5/ANAPC5抗体图片
产品货号:
Z11295
中文名称:
APC5/ANAPC5抗体
英文名称:
Anti-APC5/ANAPC5 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-APC5/ANAPC5 Antibody
指标别名ANAPC5;APC5;Cyclosome subunit 5
克隆性Polyclonal
检验物种human,mouse,rat
应用范围ELISA,WB,IHC,IF
基因名称ANAPC5
抗体来源Rabbit
抗体类型IgG
免疫原APC5 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC5.The immunogen is located within amino acids 480 - 530 of APC5.
计算分子量85kDa
成分APC5 Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式APC5 Antibody is affinity chromatography purified via peptide column.
浓度1mg/mL
产品形态溶液
保存条件4℃可保存3个月,-20℃可保存1年。
背景资料Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis.APC5 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C),a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.APC/C is responsible for degrading anaphase inhibitors,mitotic cyclins,and spindle-associated proteins ensuring that events of mitosis take place in proper sequence.The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines,suggesting that they perform their functions as part of a complex.While little is known of APC5,it is thought that APC5 associates with other APC/C components APC1,APC4,and CDC23 interdependently,such that loss of any one subunit reduces binding between the remaining three.
Uniprot IDQ9UJX4
基因名全称Anaphase promoting complex subunit 5
蛋白名全称Anaphase promoting complex subunit 5
推荐稀释比APC5 antibody can be used for detection of APC5 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested.

相关搜索:APC5/ANAPC5抗体APC5抗体ANAPC5多抗Anti-APC5/ANAPC5 Antibody
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